Microcytic hypochromic anemia patients with thalassemia : Genotyping approach
نویسندگان
چکیده
منابع مشابه
Microcytic hypochromic anemia patients with thalassemia: genotyping approach.
BACKGROUND Microcytic hypochromic anemia is a common condition in clinical practice, and alpha-thalassemia has to be considered as a differential diagnosis. AIMS This study was conducted to evaluate the frequency of alpha-gene, beta-gene and hemoglobin variant numbers in subjects with microcytic hypochromic anemia. SETTING AND DESIGNS Population-based case-control study in the Iranian popul...
متن کاملErythrocyte Catalase Activity in More Frequent Microcytic Hypochromic Anemia: Beta-Thalassemia Trait and Iron Deficiency Anemia
Most common microcytic hypochromic anemias are iron deficiency anemia (IDA) and β-thalassemia trait (BTT), in which oxidative stress (OxS) has an essential role. Catalase causes detoxification of H2O2 in cells, and it is an indispensable antioxidant enzyme. The study was designed to measure erythrocyte catalase activity (ECAT) in patients with IDA (10) or BTT (21), to relate it with thalassemia...
متن کاملEvaluation of Alpha-Thalassemia Mutations in Cases with Hypochromic Microcytic Anemia: The İstanbul Perspective
OBJECTIVE Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes. Mutations could be either more commonly deletional or non-deletional. As some deletions (3.7 and 4.2) cause α+-thalassemia, some cause (-20.5, MED, THAI, FIL) α0 -thalassemia. The aim of this study was to determine alpha thalassemia mutations in patients with unsolved hypochromic microcytic ...
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The group of 17 irradiated rats including the animal that produced anemic progeny (X2) belonged to a stock of rats randomly bred in our laboratory since 1930. The X2 female was one of five females in a litter, which were X-irradiated under conditions reported earlier (SLADICSIMIC et al. 1963). All irradiated females were mated with normal males from the stock and brother-sister matings for each...
متن کاملMicrocytic hypochromic anemia in idiopathic pulmonary hemosiderosis: a diagnostic pitfall.
Idiopathic pulmonary hemosiderosis (IPH) is a rare, life-threatening disease of uncertain etiology, characterized by recurrent intra-alveolar hemorrhages and usually afflicting young adults or children(l). Symptoms of lung hemorrhage are often few and atypical(2). Consequently, the condition may go unrecognized for a few years or months, presenting as recurrent iron deficiency anemia with no ac...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Sciences
سال: 2009
ISSN: 0019-5359
DOI: 10.4103/0019-5359.49286